SIDE-EFFECTS OF VIOXX
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Vioxx was a non- steroidal anti- inflammatory drug, made by Merck and Co. It was marketed between the years 1999 to 2004. It was used to relieve patients, mainly adults, from the pain and discomforts of osteoarthritis and rheumatoid arthritis. Though it carried a label claiming that it was safe for the stomach and liver, in some cases Vioxx did result in bleeding in the stomach and liver.
The drug was ultimately recalled because it caused problems associated with heart. People taking Vioxx were at an increased risk of heart- attack, stroke or other cardiovascular diseases. In 2004, under pressure from the FDA, Merck pulled the drug off the market worldwide, voluntarily.
The minor side effects of the drug were:
Giddiness orr
Lethargy or weakness orr
Loose stools.
In the event of the above mentioned side effects, it was important to discuss the same with your practitioner; however discontinuing the drug was not required.
The major side effects of the drug were so adverse, that they were distinguished as per the various systems of the human body, like the renal system, the nervous system and so on. The same has been explained in details as below:
In Cardiovascular System- it could have caused:-
Irregular heartbeat orr
Palpitations orr
Venous insufficiency orr
In the Digestive System- it could have caused:
Acid reflux orr
Constipation orr
Symptoms of gas in digestive tract orr
In the Immune System- it could have caused:
Hypersensitivityr
Insect bite reactionr
Allergyr
In the Musculoskeletal System: it could have causedr
Pain in arms, legs or other parts of the bodyr
Cartilage disturbancer
Muscular cramp or disorder or weaknessr
In the Nervous System: it could have caused:
Hypesthesia
Insomnia
Vertigor
In the Respiratory System: it could have caused:
Asthma
Coughr
Pulmonary congestionr
In the ENT System i.e. Ears, Eyes, Nose and Throat: it could have caused:
Blurred visionr
Dry throatr
Nasal congestionr
Ophthalmic injection or optic pain.
In the Urogenital System: it could have caused:
Breast massr
Menopausal systemr
Vaginitis
Additional side effects hampering the other functionalities of the body can be summed up as:
To the metabolism and nutrition: It could have caused:
A change in appetiter
Hypercholesterolemiar
Weight gainr
To the psychiatric: It could have caused:
Anxiety
Depressionr
Mental acuity decreasedr
To the skin and skin appendages: it could have causedr
Abrasionr
Nail unit disorderr
To the body as a whole: it could have caused:
Abdominal distension or tende
essr
Chest painr
Feverr
Fluid retention and so on.
This is not an exhaustive list of all the adverse effects the drug could cause, but it includes most of them. Congestive heart failure, herpes, gastric ulcers, hypersensitivity, hyponatremia, aggravated epilepsy , photosensitive reactions and acute renal failures were amongst the most serious side effects which were reported, albeit rarely, being reported in an estimated 0.1% of the patient population taking the drug.
For More Information Visit: http://www.unsafedrugs.com/1177/side-effects-of-vioxx
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