Alfa Chemistry Provides Fluorophores for the Synthesis of Small-Molecule Fluorescent Probes

As the popularity of small-molecule fluorescent probes enhances, the demand for fluorophores also rises. In a recent statement, Alfa Chemistry announced the release of varieties of fluorophores, which are mainly used for synthesizing small-molecule fluorescent probes and as a tool widely utilized in bioanalysis, environmental monitoring, food detection, and clinical disease diagnosis. Fluorescent probes generally consist of a fluorophore, which is its heart, a ligand that binds to a specific receptor with high affinity, and a spacer that connects the recognition group to the fluorescent group. “At present, we provide different types of fluorophores, including BODIPY dyes, cyanine dyes, rhodamine dyes, fluorescein dyes, and alike. They can be used for a wide range of purposes, among which synthesis of small-molecule fluorescent probes is most commonly seen,” says the Marketing Chief of Alfa Chemistry. BODIPY fluorophores Boron dipyrromethene (BODIPY) fluorescent materials are novel fluorophores with high fluorescence quantum yield, high molar extinction coefficient and excellent photo-stability. BODIPY fluorophores provided by Alfa Chemistry include but not limit to: BDOIPY-osu (CAS 1025119–04–3), 1,3,5,7-tetramethyl-2,6-diethyl-8-(4-carboxyphenyl) BODIPY (CAS 1033273–62–9), azido-bodipy-FL-510 (CAS 1048369–35–2), 3-bodipy-propanoic acid methyl ester (CAS 1242057–00–6), bodipy isothiocyate (CAS 1349031–04–4), BDPFL azide (CAS 1379771–95–5), etc. Cyanine fluorophore Cyanine fluorophore and its derivatives are mainly used in exploring dye-sensitized solar cells (DSSC), textile, probe, and other fields. To name just a few here: sulfo-cy3-yne (CAS 1010386–62–5), cyanine5 NHS ester (CAS 1032678–42–4), cy3 NHS ester (CAS 1032815–92–1), azido-cy5 (CAS 1048022–24–7), sulfo cy3 carboxylic acids(methyl) (CAS 1121756–11–3), sulfo-cy5 carboxylic acid (CAS 1121756–16–8), etc. Rhodamine fluorophores As one of the most common Xanthene fluorophores, rhodamine fluorophores are widely researched and used as fluorescent probes in molecular biology, dye lasers, and photosensitizers of dye-sensitized solar cells. Some of these chemicals are: azido-ROX (CAS 1048022–18–9), azido-R6G (CAS 1144503–47–8), TMRM (CAS 115532–50–8), rhodamine 101 inner salt (CAS 116450–56–7), ROX NHS ester,6-isomer (CAS 117491–83–5), carboxy rhodamine110-PEG3-azide (CAS 1536327–95–3), 5-TAMRA maleimide (CAS 154480–30–5), etc. Fluorescein fluorophores As another type of xanthene fluorescent dyes, fluorescein fluorophores is widely used in modern biology, biochemistry and medical research. Some of these chemicals are: 5-FITCDA (CAS 118378–76–0), CFDA (CAS 124387–19–5), CDCFDA (CAS 127770–45–0), 5-FITC biotin (CAS 134759–22–1), cellhunt green CMFDA[5-ChloromethylfluoresceinDiacetate] (CAS 136832–63–8), DAF-2DA (CAS 205391–02–2), fluorescein-DBCO (CAS 2054339–00–1), fluorescein-PEG6-acid (CAS 2055014–69–0), fluorescein-PEG6-bis-NH sester (CAS 2055105–59–2), etc. Besides, hybrid fluorophores, coumarin fluorophores, naphthalimide fluorophores, and other fluorophores are also readily obtainable at Alfa Chemistry. Please visit https://photochem.alfa-chemistry.com/products/common-fluorophores-and-derivatives.html to learn more.