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Allergies - Supporting the Natural Corticosteroid Response

Topic: NutritionPublished July 19, 2007

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Corticosteroid drugs are a popular treatment for many allergic conditions. The adrenal glands are also capable of producing corticosteroid hormones - which have some of the same anti-allergy properties as the drugs. Many allergic individuals may have low adrenal function and therefore don't produce enough corticosteroids which help neutralize allergic reactions.

Think you don't have low adrenal function?? Consider that the adrenal glands are our primary modulators of stress. Our fast-paced society/lifestyle causes a fair amount of stress - not to mention that which we put upon ourselves. Stress depletes several nutrients faster such as Vitamin B5, B6 and Vitamin C, Magnesium and Zinc.

B Vitamins - A key nutrient is pantothenic acid, aka B5. A deficiency of pantothenic acid causes the adrenal glands to not be able to produce corticosteroid hormones. However, research has shown that supplementation with B5 has significantly increased the production of corticosteroids, therefore decreasing histamine production, in both human and animal studies. Suggested doses are 300-2000mg daily. Supplemental B6 of 50mg and Sublingual B12 2000mcg can also be helpful. Note that these doses may be helpful over a period of time, not within a few days.

Vitamin C - Another key nutrient is Vitamin C. Since Vitamin C is water-soluble (as is B5), our bodies are in constant need. To intensify that, Vitamin C is depleted whenever the adrenal glands secrete corticosteroids. So Vitamin C supplementation helps to increase the natural steroid production and decreases the body's sensitivity to the antigen. One researcher stated that, "Allergic and sensitivity reactions are frequently and sometimes completely blocked by massive doses of ascorbate (Vitamin C)." {Cathcart RF3d, Med Hypotheses (1986) 21(3);pp 307-21}. The suggested daily dose is 2000mg (divided doses) or more for those with allergies.

In addition to the above vital nutrients, 300mg of Stinging Nettle was rated higher than a placebo in reducing allergic symptoms after taking it for one week. Among 98 subjects with allergic rhinitis, 58% rated it moderately or highly effective and 48% indicated it was equally or more effective than medicines used previously. (Brinker F, Botanical Research Summaries (1989), pp4-36.)

Bioflavonoids and Quercetin inhibit allergy-induced histamine release. Quercetin has also been shown to decrease the formation of leukotrienes (inflammatory chemicals) which may be involved in the allergic process. Wild Cherry Bark, 420mg daily, in divided doses can help to soothe an irritated throat and bronchial spasms.

In addition to supporting your own corticosteroid response, there are many natural supplements and homeopathic remedies which can help relieve allergic symptoms. Ask your favorite nutrition store what they suggest. Consider a combination homeopathic formula for allergies versus a single remedy unless you have worked with someone trained in homeopathy. There are also several homeopathic nasal and sinus sprays which can help with more immediate relief of symptoms.

Article author

About the Author

Theresa Groskop is a Certified Nutritionist at Natural Healthy Concepts. She works with individuals in nutritional counseling and general wellness. For more http://www.naturalhealthyconcepts.com information visit

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