Article

Cause Of Inflammation And Pain In The Body

Topic: Pain ManagementPublished September 30, 2011

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Celebrex is a nonsteroidal antiinflammatory drug that is used to treat arthritis, pain, menstrual cramps, and colonic polyps. Prostaglandins are chemicals that are important contributors to the inflammation of arthritis that causes pain, fever, swelling and tenderness. Celecoxib blocks the enzyme that makes prostaglandins (cyclooxygenase 2), resulting in lower concentrations of prostaglandins. As a consequence, inflammation and its accompanying pain, fever, swelling and tenderness are reduced. Celecoxib differs from other NSAIDs in that it causes less inflammation and ulceration of the stomach and intestine (at least with short-term use) and does not interfere with the clotting of blood. This medicine works by reducing hormones that cause inflammation and pain in the body. Stomach upset or gas may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor immediately if any of these unlikely but serious side effects occur: severe headache, unexplained weight gain, swelling of the hands or feet, pain/swelling/warmth in the groin/calf, change in amount of urine, difficult/painful swallowing. Precaution 1) Do not use this medicine if you are allergic to it or to its ingredient.rn2) Do not use Celebrex just before or after heart bypass surgery.rn3) Celebrex may cause life-threatening heart or circulation problems such as heart attack or stroke, especially if you use it long term.rn4) Do not use not use Celebrex if you are allergic to celecoxib, or if you have a history of allergic reaction to aspirin, sulfa drugs, or other NSAIDs. Before taking Celebrex medicine you should inform your doctor if your are suffering from a history of heart attack, stroke, or blood clot, heart disease, congestive heart failure, high blood pressure, a history of stomach ulcers or bleeding, liver or kidney, disease, a seizure disorder such as epilepsy, asthma, polyps in your nose and a bleeding or blood clotting disorder. Do not take this medicine if you are pregnant or breastfeeding mother as use of this medicine by pregnant and breastfeeding mother may harm the health of unborn baby or nursed child. Side Effect of Celebrex Every medicine has its own side effects. Many medicines have some common to serious side effects. This medicine also has some side effect like bleeding stomach ulcers, black bowel movements, bloody vomit, burning stomach pain,nausea, vomiting, tiredness, loss of appetite, itching, yellow skin or eyes, dark urine and flu-like symptoms. Drug Interaction Before taking this medicine you should inform your doctor if you are taking any prescription, non prescription and herbal medicine as use of this medicine may cause some serious drug interaction. Do not use celebrex medicine with ACE-inhibitors like captopril, enalapril maleate, and lisinopril, blood thinning agents such as warfarin sodium and furosemide

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