CD Formulation Is Able to Conduct API-Excipient Compatibility Analysis
As a service provider for custom pharmaceutical formulation projects, CD Formulation announces today that it is able to conduct API-excipient compatibility analysis service for clients across the globe with drug development demands.
“The testing and analysis of the API-excipient compatibility is an extremely critical step in the drug preformualtion stage. We know that a drug substance is usually more stable by itself than in a formulation with excipients. Inappropriate dosage forms can interact with drug substances and in worst cases can even cause drug degradation,” says the Marketing Chief of CD Formulation.
“With strong expertise and in-depth understanding of physical and chemical API-excipient interactions, our scientists can assist clients to select the most appropriate excipients in dosage form design. Our comprehensive services have many benefits, such as to make the drug being developed easy to administer, to promote drug release and bioavailability, and to extend its shelf life,” the spokesperson further explains.
Techniques used in the analysis of API-excipient compatibility include thermal methods of analysis, spectroscopic technique, microscopic technique, and chromatography. And these techniques cover the following wide-ranged methods: differential scanning calorimetry (DSC), isothermal microcalorimetry, hot stage microscopy (HSM), vibrational spectroscopy, powder X-ray diffraction (PXRD), solid-state nuclear magnetic resonance spectroscopy (ss NMR), scanning electron microscopy (SEM), self-interactive chromatography (SIC), thin layer chromatography (TLC), and high-performance liquid chromatography (HPLC).
With both expertise and advanced equipment, CD Formulation’s API-excipient compatibility analysis service can help assess the risk of API-excipient interactions before formulation development, thus saving both time and cost for clients.
In addition to API-excipient compatibility analysis, the company is also skilled in other customized preformulation services, such as crystallinity determination, amorphous content determination, hygroscopicity evaluation, particle size analysis, moisture content determination, solubility analysis, LogP/LogD/pKa analysis as well as stability analysis. For more relevant information, please visit: https://www.formulationbio.com/api-excipient-compatibility.html or email us directly at contact@formulationbio.com.
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