How can Orchitis Cause Male Infertility?

Testicles are very important for reproduction. If the testicles develop into lesions, it will affect men's fertility. Orchitis is one of the diseases of the male reproductive system, which is a manifestation of testicular lesions. Therefore, orchitis will affect sperm production and even lead to male infertility. Testicles are the only spermatogenic organ in men. Without testicles, there will be no children. If testicular lesions occur, it will affect men's fertility. Orchitis is one of the testicular lesions. Testicular inflammation is bound to affect spermatogenesis, resulting in male infertility. 1. Cause seminal duct obstruction When orchitis is caused by gonococcus, Mycobacterium tuberculosis and other pathogens, it will produce inflammatory reaction and damage sperm and easily cause the narrowing or blockage of the epididymal lumen, resulting in obstructive azoospermia. 2. Form anti-sperm antibodies Orchitis is also a significant cause of sperm antibodies. When testicular inflammation occurs, immune cells and humoral immune substances enter the inflamed epididymal canal to produce an immune response to pathogens and form antibodies, which will affect the forward movement of sperm. 3. Reduce sperm motility When orchitis occurs, some pathogens can directly damage sperm in the testicular canal, inhibit sperm activity, or agglutinate sperm, and then reduce its activity. Some pathogens will adsorb on the sperm surface, reducing or even losing their motility. 4. Significantly increase sperm mortality When bodyguards such as leukocytes and macrophages destroy pathogens, they may also accidentally injure or kill sperm, regardless of good or bad. A large number of metabolites produced by inflammatory reaction will also poison sperm, change the living environment of sperm, reduce sperm motility, increase dead sperm, increase the rate of abnormal sperm and reduce the number of sperm, which can lead to male infertility. Orchitis can lead to male infertility, so it needs active treatment. General treatment Lying in bed, holding up the affected scrotum and local cold compress can help alleviate symptoms and avoid the spread of inflammation. Men with scrotal skin redness and swelling can use a local wet compress with 25% - 50% magnesium sulfate solution. If the long-term indwelling of the catheter causes orchitis, the catheter should be removed as soon as possible. If the catheter must be retained, the catheter as thin as possible should also be replaced, and remove the urethral secretions in time. Ligation of bilateral vas deferens during prostatectomy is also helpful to prevent orchitis. Medication treatment Antibiotics should be used throughout the body for bacterial orchitis. When the effect of antibiotics is poor, or the symptoms occur repeatedly and become chronic orchitis, men can choose patent herbal medicine Diuretic and Anti-inflammatory Pill for treatment. It can effectively eliminate symptoms and cure orchitis. Moreover, it can improve the patient's resistance and reduce the probability of recurrence. Surgical treatment After the formation of testicular abscess, antibiotic treatment is challenging to be effective. Incision and drainage of the abscess are very easy to form postoperative testicular skin sinus. If the abscess is extensive, testicular atrophy is inevitable. Therefore, orchiectomy is feasible for these patients. Incision of tunica albuginea can cause immune sperm overflow and aggravate the inflammatory reaction. Therefore, incision and decompression of testicular tunica albuginea should be particularly careful. Most acute orchitis can be quickly controlled and cured after timely and effective treatment. A few patients with untimely and incomplete treatment can turn into chronic orchitis. A very few patients will have testicular necrosis and need to remove the testicles. Some patients may have different degrees of testicular contraction after 1-2 months.